Package: roben
Type: Package
Title: Robust Bayesian Variable Selection for Gene-Environment
        Interactions
Version: 0.1.3
Authors@R: c(person(given = "Jie",
				  family = "Ren",
				  role = c("aut", "cre"),
				  email = "renjie0910@gmail.com"),
		   person(given = "Fei",
				  family = "Zhou",
				  role = "aut"),
		   person(given = "Xiaoxi",
				  family = "Li",
				  role = "aut"),
		   person(given = "Cen",
				  family = "Wu",
				  role = "aut"))
Maintainer: Jie Ren <renjie0910@gmail.com>
Description: Gene-environment (G×E) interactions have important
        implications to elucidate the etiology of complex diseases
        beyond the main genetic and environmental effects. Outliers and
        data contamination in disease phenotypes of G×E studies have
        been commonly encountered, leading to the development of a
        broad spectrum of robust penalization methods. Nevertheless,
        within the Bayesian framework, the issue has not been taken
        care of in existing studies. We develop a robust Bayesian
        variable selection method for G×E interaction studies. The
        proposed Bayesian method can effectively accommodate
        heavy-tailed errors and outliers in the response variable while
        conducting variable selection by accounting for structural
        sparsity. In particular, the spike-and-slab priors have been
        imposed on both individual and group levels to identify
        important main and interaction effects. An efficient Gibbs
        sampler has been developed to facilitate fast computation. The
        Markov chain Monte Carlo algorithms of the proposed and
        alternative methods are efficiently implemented in C++.
Depends: R (>= 4.0.0)
License: GPL-2
Encoding: UTF-8
LazyData: true
LinkingTo: Rcpp, RcppArmadillo
Imports: Rcpp, glmnet, stats
Suggests: testthat (>= 3.0.0), covr
URL: https://github.com/jrenstat/roben
BugReports: https://github.com/jrenstat/roben/issues
Config/testthat/edition: 3
Config/roxygen2/version: 8.0.0
Repository: https://jrenstat.r-universe.dev
Date/Publication: 2026-05-20 23:06:19 UTC
RemoteUrl: https://github.com/jrenstat/roben
RemoteRef: HEAD
RemoteSha: 69c6d903f2cb9e8414dae81aaa8ac142dfc57ff1
NeedsCompilation: yes
Packaged: 2026-06-19 06:55:05 UTC; root
Author: Jie Ren [aut, cre],
  Fei Zhou [aut],
  Xiaoxi Li [aut],
  Cen Wu [aut]